20 Scopus citations


Osteoporosis, a global health problem, is now frequently recognized to be secondary to alterations in the pituitary-bone axis. This review examines the current evidence for how dysregulation of the pituitary-bone axis leads to osteoporotic bone loss. Specifically, perimenopausal bone loss in the context of follicle-stimulating hormone action, and hyperthyroid bone loss in the context of thyroid-stimulating hormone action are explored. From the reviewed scientific findings, recommendations for early diagnosis and better clinical management of bone loss are made.

Original languageEnglish
Pages (from-to)205-211
Number of pages7
JournalCurrent Osteoporosis Reports
Issue number4
StatePublished - Dec 2010


  • Bone loss
  • Estrogen
  • FSH
  • Menopause
  • Osteoclast
  • Osteoporosis
  • TSH


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