The role of endoscopy in small bowel neuroendocrine tumors

Ji Yoon Yoon, Nikhil A. Kumta, Michelle Kang Kim

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Small bowel neuroendocrine tumors (NETs) represent approximately one-third of NETs of the gastrointestinal tract, and their incidence is increasing. When determining if endoscopic resection is appropriate, endoscopic ultrasound is used to assess the lesion size and depth of invasion for duodenal NETs. A number of techniques, including endoscopic mucosal resection (EMR), band-assisted EMR (band-EMR), endoscopic submucosal dissection (ESD), and over-the-scope clip-assisted endoscopic full-thickness resection (EFTR), have been studied; however, the best technique for endoscopic resection remains unclear. The vast majority of currently available data are retrospective, and prospective studies with longer follow-up times are required. For jejunal and ileal NETs, endoscopic techniques such as video capsule endoscopy (VCE) and balloon enteroscopy (BE) assist in diagnosis. This includes localization of the primary NET in metastatic disease where initial workup has been negative, and the identification of multifocal disease, which may change management and prognostication.

Original languageEnglish
Pages (from-to)818-824
Number of pages7
JournalClinical Endoscopy
Issue number6
StatePublished - Nov 2021


  • Carcinoid tumors
  • Endoscopy
  • Neuroendocrine tumors
  • Small intestine


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