The Role of Echocardiography in the Detection of Chemotherapy-Induced Cardiotoxicities

P. T. Gleason, J. C. Lisko, S. Lerakis

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Advances in chemotherapy and radiation treatment have drastically improved mortality associated with numerous malignancies. This is counterbalanced by the short- and long-term cardiotoxic effects of cancer therapy. Given the significant morbidity and mortality associated with cardiovascular complications of cancer therapy, strategies for early detection, and prevention of cardiotoxicity are needed. While the exact timing and method of screening for cardiotoxicity remains uncertain, an ideal screening test would be widely available, radiation free, and relatively inexpensive. Echocardiography (echo) is the most widely used, noninvasive, radiation-free test of cardiac morphology and function. Advances in echocardiographic techniques, such as 3D echocardiography and speckle tracking and strain imaging, may allow for the successful detection and treatment of subclinical cardiac dysfunction prior to overt cardiomyopathy and heart failure.

Original languageEnglish
Title of host publicationCardio-Oncology
Subtitle of host publicationPrinciples, Prevention and Management
PublisherElsevier Inc.
Pages267-278
Number of pages12
ISBN (Electronic)9780128035535
ISBN (Print)9780128035474
DOIs
StatePublished - 2017
Externally publishedYes

Keywords

  • Cardio-oncology
  • Chemotherapy
  • Echocardiography
  • Ejection fraction
  • Global longitudinal strain
  • Speckle tracking

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