The role of directional atherectomy in critical-limb ischemia

Prakash Krishnan, Arthur Tarricone, Simon Chen, Samin Sharma

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Background: Our aim was to review the current literature of the use of directional atherectomy (DA) in the treatment of lower extremity critical-limb ischemia. Methods: A search for relevant literature was performed in PubMed and PubMed Central on 16 April 2020, sorted by best match. Three searches across two databases were performed. Articles were included that contained clinical and procedural data of DA interventions in lower extremity critical-limb ischemia patients. All studies that were systematic reviews were excluded. Results: Eleven papers were included in this review. Papers were examined under several parameters: primary patency and secondary patency, limb salvage/amputation, technical/procedural success, complications/periprocedural events, and mean lesion length. Primary and secondary patency rates ranged from 56.3% to 95.0% and 76.4% to 100%, respectively. Limb salvage rates ranged from 69% to 100%. Lesion lengths were highly varied, representing a broad population, ranging from 30 ± 33 mm to 142.4 ± 107.9 mm. Conclusions: DA may be a useful tool in the treatment of lower extremity critical-limb ischemia.

Original languageEnglish
JournalTherapeutic Advances in Cardiovascular Disease
StatePublished - 2021


  • Critical Limb Ischemia
  • Directional Atherectomy
  • Peripheral Artery Disease


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