The retinoids in acne

D. E. Bushnell, S. Billstein, R. A. Schwartz, W. C. Lambert

Research output: Contribution to journalArticlepeer-review


Vitamin A is essential for growth and development, reproduction and vision in humans. Chemical modification of vitamin A has yielded compounds showing therapeutic promise in skin and neoplastic diseases. The medicinal use of retinoids (vitamin A and its derivatives) is limited by the toxicity associated with this group of compounds. One retinoid, 13-cis-retinoic acid, has proved to be quite effective in the treatment of severe recalcitrant cystic acne under conditions in which toxicity is manageable.

Original languageEnglish
Pages (from-to)221-226
Number of pages6
JournalAmerican Family Physician
Issue number3
StatePublished - 1984
Externally publishedYes


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