The response of joints to impact loading - II In vivo behavior of subchondral bone

Sheldon R. Simon, Eric L. Radin, Igor L. Paul, Robert M. Rose

Research output: Contribution to journalArticlepeer-review

163 Scopus citations

Abstract

The knee joints of live guinea pigs, subjected to repeated longitudinal impaction, developed obvious cartilage degeneration over a 3 week period. In vitro tests had previously shown that articular cartilage is particularly susceptible to injury from impact loading and that subchondral bone acts as a cushion to protect the overlying cartilage from damage during such loading. Associated with, and slightly preceding the earliest cartilage changes, as judged histochemically, was a stiffening of the underlying subchondral bone. The bone stiffness measurements returned to within the normal range as the cartilage degeneration progressed.

Original languageEnglish
Pages (from-to)267-270,IN3,271-272
JournalJournal of Biomechanics
Volume5
Issue number3
DOIs
StatePublished - May 1972
Externally publishedYes

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