The renaissance of GSK3

  • Philip Cohen
  • , Sheelagh Frame

Research output: Contribution to journalReview articlepeer-review

1398 Scopus citations

Abstract

Glycogen synthase kinase 3 (GSK3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. The study of the substrate specificity and regulation of GSK3 activity has been important in the quest for therapeutic intervention.

Original languageEnglish
Pages (from-to)769-776
Number of pages8
JournalNature Reviews Molecular Cell Biology
Volume2
Issue number10
DOIs
StatePublished - Oct 2001
Externally publishedYes

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