TY - JOUR
T1 - The radioisotope renogram in normal subjects
AU - Wedeen, Richard P.
AU - Goldstein, Marvin H.
AU - Levitt, Marvin F.
PY - 1963/6
Y1 - 1963/6
N2 - The alterations in the contour of the I131-hippuran renogram recorded in normal subjects under conditions of varying rates of urine flow, PAH loading, position changes and ureteral obstruction are described. In addition, patients with a unilateral non-functioning kidney or nephrectomy were studied after the administration of I131-hippuran and I131-human serum albumin. The physiologic basis of the tracing is discussed and a quantitative method of analysis is presented. The renogram contour appears to be dependent upon the rates of urine flow and tubular transport. Sensitivity to changes in urine flow appears to be too low to permit accurate measurement of flow from the separate kidneys by this technic.
AB - The alterations in the contour of the I131-hippuran renogram recorded in normal subjects under conditions of varying rates of urine flow, PAH loading, position changes and ureteral obstruction are described. In addition, patients with a unilateral non-functioning kidney or nephrectomy were studied after the administration of I131-hippuran and I131-human serum albumin. The physiologic basis of the tracing is discussed and a quantitative method of analysis is presented. The renogram contour appears to be dependent upon the rates of urine flow and tubular transport. Sensitivity to changes in urine flow appears to be too low to permit accurate measurement of flow from the separate kidneys by this technic.
UR - https://www.scopus.com/pages/publications/11544300146
U2 - 10.1016/0002-9343(63)90085-8
DO - 10.1016/0002-9343(63)90085-8
M3 - Article
C2 - 13999442
AN - SCOPUS:11544300146
SN - 0002-9343
VL - 34
SP - 765
EP - 774
JO - American Journal of Medicine
JF - American Journal of Medicine
IS - 6
ER -