The Quest for a Universal Flu Vaccine: Headless HA 2.0

Florian Krammer

Research output: Contribution to journalShort surveypeer-review

46 Scopus citations


Two recent publications report the design of immunogens based on the conserved stalk domain of the influenza virus hemagglutinin. These new "headless" hemagglutinin constructs recapitulate the epitopes recognized by broadly neutralizing antibodies and induce broadly protective/heterosubtypic immunity in animal models, bringing us a step closer to "universal" influenza virus vaccines.

Original languageEnglish
Article number1347
Pages (from-to)395-397
Number of pages3
JournalCell Host and Microbe
Issue number4
StatePublished - 14 Oct 2015


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