The PROTAC selectively degrading Bcl-xL represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth

Shaoqing Zhang, Yue Chen, Zhongli Xu, Jun Yang, Renhong Sun, Juan Wang, Yiming Sun, Biao Jiang, Xiaobao Yang, Wenfu Tan

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Medicine and Dentistry

Biochemistry, Genetics and Molecular Biology

Immunology and Microbiology

Pharmacology, Toxicology and Pharmaceutical Science