Abstract
Comparison of NH2-terminal protein sequence from the rat OX-44 antigen with the sequence of the human CD37 antigen deduced from a cDNA clone shows that these antigens are species homologues. The CD37 sequence is 244 amino acids in length and lacks a conventional leader sequence. The molecule is likely to have an NH2-terminal cytoplasmic domain followed by three transmembrane sequences that lie within the first 110 amino acids. The rest of the molecule is hydrophillic and contains three sites for N-linked glycosylation.
Original language | English |
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Pages (from-to) | 1497-1502 |
Number of pages | 6 |
Journal | Journal of Experimental Medicine |
Volume | 169 |
Issue number | 4 |
DOIs | |
State | Published - 1989 |
Externally published | Yes |