The prevention and genetics of pancreatic cancer: A programmatic approach

Aimee L. Lucas, Michelle M. Chang, Marla D. Lipsyc, Harold Frucht

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations

Abstract

Pancreatic cancer (PC) is typically a fatal disease due to its rapid growth and the lack of early diagnostic techniques. Because approximately 10% of PCs are attributable to a hereditary susceptibility, identifying and studying patients with a family history of PC or known genetic predisposition to PC can improve the prevention, diagnosis, and treatment of PC. A skilled team of study investigators, physicians, genetic counselors, and data managers must work with patients and families to con fidentially store and organize data from PC patients and high-risk patients. This data, collected in conjunction with patients' tissue and blood specimens, will contribute to the understanding of the biology, etiology, and epidemiology of PC, and can ultimately improve screening and management for patients with an underlying hereditary predisposition to PC.

Original languageEnglish
Title of host publicationPancreatic Cancer
Subtitle of host publicationMethods and Protocols
PublisherHumana Press Inc.
Pages205-214
Number of pages10
ISBN (Print)9781627032865
DOIs
StatePublished - 2013

Publication series

NameMethods in Molecular Biology
Volume980
ISSN (Print)1064-3745

Keywords

  • Biorepository
  • Cancer prevention
  • Database
  • Genetic testing
  • Hereditary pancreatic cancer
  • Pancreatic cancer
  • Registry
  • Screening
  • Surveillance
  • Tissue bank

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