@article{f9f5fec897d24f51aa1111c0cd8ba1fe,
title = "The prevalence of diabetes mellitus is increased in relatives of patients with a non-affective psychotic disorder",
abstract = "Patients with schizophrenia are more likely to develop diabetes mellitus (DM) compared to the general population. In relatives, however, an increased rate of DM has not consistently been reported. In this study, we compared DM rates in 1740 unaffected first- and second-/third-degree relatives of patients with a non-affective psychotic disorder to 1271 control subjects, by administering the Family Interview for Genetic Studies (FIGS). The prevalence of DM (6.1\%) was increased in the relatives of patients as compared to the relatives of the healthy subjects (3.6\%, OR = 1.6, p = 0.007). Our findings support the hypothesis of a familial, possibly genetic, link between DM and non-affective psychotic disorders.",
keywords = "Diabetes, Non-affective psychotic disorder, Relatives",
author = "\{Van Welie\}, H. and Derks, \{E. M.\} and Verweij, \{K. H.\} and \{De Valk\}, \{H. W.\} and Kahn, \{R. S.\} and W. Cahn",
note = "Funding Information: This work is supported by the Netherlands Scientific Organization (NWO; project number 451-080-010 ; PI E.M. Derks). We are grateful for the generosity of time and effort by the patients and their families, healthy subjects, and all researchers who made this GROUP project possible. Funding Information: The infrastructure for the GROUP study is funded through the Geestkracht programme of the Dutch Health Research Council (ZON-MW, grant number 10-000-1001), and matching funds from participating pharmaceutical companies (Lundbeck, AstraZeneca, Eli Lilly, Janssen Cilag) and universities and mental health care organizations (Amsterdam: Academic Psychiatric Centre of the Academic Medical Centre and the mental health institutions: GGZ Ingeest, Arkin, Dijk en Duin, Rivierduinen, Erasmus Medical Centre, GGZ Noord Holland Noord. Maastricht: Maastricht University Medical Centre and the mental health institutions: GGZ Eindhoven, GGZ Midden-Brabant, GGZ Oost-Brabant, GGZ Noord-Midden Limburg, Mondriaan Zorggroep, Prins Clauscentrum Sittard, RIAGG Roermond, Universitair Centrum Sint-Jozef Kortenberg, CAPRI University of Antwerp, PC Ziekeren Sint-Truiden, PZ Sancta Maria Sint-Truiden, GGZ Overpelt, OPZ Rekem. Groningen: University Medical Center Groningen and the mental health institutions: Lentis, GGZ Friesland, GGZ Drenthe, Dimence, Mediant, GGZ De Grote Rivieren and Parnassia psycho-medical centre (The Hague). Utrecht: University Medical Centre Utrecht and the mental health institutions: Altrecht, Symfora, Meerkanten, Riagg Amersfoort and Delta). ",
year = "2013",
month = feb,
doi = "10.1016/j.schres.2012.11.011",
language = "English",
volume = "143",
pages = "354--357",
journal = "Schizophrenia Research",
issn = "0920-9964",
publisher = "Elsevier B.V.",
number = "2-3",
}