The prevalence of adenocarcinoma in non-small cell lung cancer patients at Chulabhorn Hospital

Objective: To study the prevalence of the adenocarcinoma cell type in non-small cell lung cancer cases at Chulabhorn Hospital and examine the correlation between histology type and survival of patients. Materials and Methods: We examined the medical records of non-small cell lung cancer cases treated in Chulabhorn Hospital from January 2009 to December 2011. Baseline demographic data and cancer treatment information were obtained for survival analyses. Results: Among 62 cases of non-small cell lung cancer, 67.7% were the adenocarcinoma subtype. The median survival of non-small cell lung cancer cases was 11 months (95% CI; 9.0 to 18.0), 12 months in adenocarcinoma group and 7.4 months in squamous cell carcinoma group. There was statistically significant differences of survival among different histology(p=0.006). There was a slightly higher incidence of adenocarcinoma in the non-smoker group compared with the smoker group, 67.7% vs. 64.7%, respectively. Smoking status was significantly associated with histology subtype (p=0.034). Conclusion: The adenocarcinoma subtype was found in approximately two-thirds of non-small cell lung cancer cases at Chulabhorn hospital. The median survival of patients with the adenocarcinoma subtype was longer than patients with the squamous cell carcinoma subtype with statistically significant.