The potential of stem cells as an in vitro source of red blood cells for transfusion

Anna Rita Migliaccio; Carolyn Whitsett; Thalia Papayannopoulou; Michel Sadelain

doi:10.1016/j.stem.2012.01.001

The potential of stem cells as an in vitro source of red blood cells for transfusion

Anna Rita Migliaccio
, Carolyn Whitsett
, Thalia Papayannopoulou
, Michel Sadelain

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Review article › peer-review

62 Scopus citations

Abstract

Recent advances have increased excitement about the potential for therapeutic production of red blood cells (RBCs) in vitro. However, generation of RBCs in the large numbers required for transfusion remains a significant challenge. In this article, we summarize recent progress in producing RBCs from various cell sources, and discuss the hurdles that remain for translation into the clinical arena.

Original language	English
Pages (from-to)	115-119
Number of pages	5
Journal	Cell Stem Cell
Volume	10
Issue number	2
DOIs	https://doi.org/10.1016/j.stem.2012.01.001
State	Published - 3 Feb 2012

Access to Document

10.1016/j.stem.2012.01.001

Cite this

@article{44fc2534a4244bad84b987d74fa8174c,

title = "The potential of stem cells as an in vitro source of red blood cells for transfusion",

abstract = "Recent advances have increased excitement about the potential for therapeutic production of red blood cells (RBCs) in vitro. However, generation of RBCs in the large numbers required for transfusion remains a significant challenge. In this article, we summarize recent progress in producing RBCs from various cell sources, and discuss the hurdles that remain for translation into the clinical arena.",

author = "Migliaccio, \{Anna Rita\} and Carolyn Whitsett and Thalia Papayannopoulou and Michel Sadelain",

year = "2012",

month = feb,

day = "3",

doi = "10.1016/j.stem.2012.01.001",

language = "English",

volume = "10",

pages = "115--119",

journal = "Cell Stem Cell",

issn = "1934-5909",

publisher = "Cell Press",

number = "2",

}

TY - JOUR

T1 - The potential of stem cells as an in vitro source of red blood cells for transfusion

AU - Migliaccio, Anna Rita

AU - Whitsett, Carolyn

AU - Papayannopoulou, Thalia

AU - Sadelain, Michel

PY - 2012/2/3

Y1 - 2012/2/3

N2 - Recent advances have increased excitement about the potential for therapeutic production of red blood cells (RBCs) in vitro. However, generation of RBCs in the large numbers required for transfusion remains a significant challenge. In this article, we summarize recent progress in producing RBCs from various cell sources, and discuss the hurdles that remain for translation into the clinical arena.

AB - Recent advances have increased excitement about the potential for therapeutic production of red blood cells (RBCs) in vitro. However, generation of RBCs in the large numbers required for transfusion remains a significant challenge. In this article, we summarize recent progress in producing RBCs from various cell sources, and discuss the hurdles that remain for translation into the clinical arena.

UR - https://www.scopus.com/pages/publications/84856729259

U2 - 10.1016/j.stem.2012.01.001

DO - 10.1016/j.stem.2012.01.001

M3 - Review article

C2 - 22305561

AN - SCOPUS:84856729259

SN - 1934-5909

VL - 10

SP - 115

EP - 119

JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 2

ER -

The potential of stem cells as an in vitro source of red blood cells for transfusion

Abstract

Access to Document

Fingerprint

Cite this