The potential of stem cells as an in vitro source of red blood cells for transfusion

Anna Rita Migliaccio, Carolyn Whitsett, Thalia Papayannopoulou, Michel Sadelain

Research output: Contribution to journalReview articlepeer-review

60 Scopus citations

Abstract

Recent advances have increased excitement about the potential for therapeutic production of red blood cells (RBCs) in vitro. However, generation of RBCs in the large numbers required for transfusion remains a significant challenge. In this article, we summarize recent progress in producing RBCs from various cell sources, and discuss the hurdles that remain for translation into the clinical arena.

Original languageEnglish
Pages (from-to)115-119
Number of pages5
JournalCell Stem Cell
Volume10
Issue number2
DOIs
StatePublished - 3 Feb 2012

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