The Offspring of Schizophrenics: Fetal and Neonatal Deaths

Ronald O. Rieder, David Rosenthal, Paul Wender, Helene Blumenthal

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93 Scopus citations


This is the first report in a projected series on neurological development among the offspring of schizophrenics. An increased incidence of fetal and neonatal deaths is noted among offspring of schizophrenics when compared to a closely matched control group, using data collected prospectively. In many cases, no apparent reason for death was determined; in some cases, major neurological malformations were found. It is necessary to consider three possible explanations for these findings—genotype of the child, adverse intrauterine environment, and medication toxicity.

Original languageEnglish
Pages (from-to)200-211
Number of pages12
JournalArchives of General Psychiatry
Issue number2
StatePublished - Feb 1975
Externally publishedYes


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