The occurrence of antibodies to Yersinia Enterocolitica in thyroid diseases

Louis Shenkman, Edward J. Bottone

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations


With the exception of several distinct thyroid disorders whose pathogenesis have been defined, the etiology of most forms of thyroid disease is still unclear. The greatest attention has been directed towards understanding the pathogenetic mechanisms of Graves’ disease and Hashimoto’s thyroiditis, two disorders which share many pathologic and clinical similarities. Many causal factors such as (1) emotional stress, (2) genetic predisposition, (3) alterations in humoral and cell-mediated immunity, and (4) infections have been proposed for Graves’ disease and Hashimoto’s thyroiditis. The strongest evidence marshaled to date appears to implicate an immunologic pathway as the pathogenetic mechanism of these two disorders.

Original languageEnglish
Title of host publicationYersinia Enterocolitica
PublisherCRC Press
Number of pages10
ISBN (Electronic)9781351086257
ISBN (Print)0849355451, 9781315898704
StatePublished - 1 Jan 2018


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