The nucleoprotein of influenza A virus inhibits the innate immune response by inducing mitophagy

Keyphrases

• Mitophagy 100%
• Nucleoprotein 100%
• Influenza Virus 100%
• Innate Immune Response 100%
• Co-immunoprecipitation (co-IP) 27%
• Virus Replication 27%
• Virus 18%
• Mitochondria 18%
• Autophagy Pathway 18%
• Autophagy 18%
• SQSTM1 18%
• Cargo Receptor 18%
• NBR1 18%
• Tollip 18%
• Mitochondrium 18%
• Interferon-α (IFN-α) 9%
• Carbonyl 9%
• Post-infection 9%
• Novel Mechanism 9%
• Polymerase 9%
• Host Immune Response 9%
• Homeostasis 9%
• Replication in Vitro 9%
• H1N1 Virus 9%
• Actin 9%
• Sendai Virus 9%
• Antiviral Activity 9%
• Retinoic Acid-inducible Gene I (RIG-I) 9%
• Innate Immunity 9%
• ATG7 9%
• Enhanced Green Fluorescent Protein (eGFP) 9%
• Chlorophenyl 9%
• Inner Mitochondrial Membrane 9%
• Anchoring Proteins 9%
• LAMP2 9%
• Viral Ribonucleoprotein 9%
• TOMM20 9%
• COXIV 9%
• Multiplicity of Infection 9%
• Tubulin 9%
• Microtubule-associated Protein 1 Light Chain 3 9%
• MAP1LC3B 9%
• LAMP1 9%
• Human Kidney 9%
• Glyceraldehyde-3-phosphate Dehydrogenase 9%
• Lethal Dose 9%
• Outer Mitochondrial Membrane 9%
• Cyanide 9%
• RNA Sensors 9%
• GAPDH 9%
• Hydrazone 9%
• Mitochondrial Antiviral Signaling Protein 9%
• 4′,6-diamidino-2-phenylindole 9%
• Infectious Dose 9%
• Red Fluorescent Protein 9%
• Cytochrome c Oxidase 9%
• Toll-interacting Protein 9%
• ATG12 9%
• Mitochondrial Division Inhibitor 1 9%
• Mdivi-1 9%
• COX4 9%
• EID50 9%

Biochemistry, Genetics and Molecular Biology

• Nucleoprotein 100%
• Influenza A Virus 100%
• Mitophagy 100%
• Innate Immunity 100%
• Autophagy 36%
• Virus Replication 27%
• Mitochondrion 18%
• Mitochondrial Membrane Transport Protein 18%
• Immunoprecipitation 18%
• Synapsin I 18%
• Translocase 18%
• NBR1 18%
• Carrier Protein 18%
• Homeostasis 9%
• RNA 9%
• Polymerase 9%
• Microtubule-Associated Protein 9%
• Immune Response 9%
• Light Chain 9%
• Sendai Virus 9%
• Influenza Virus 9%
• Influenza A Virus (H1N1) 9%
• RIG-I 9%
• Green Fluorescent Protein 9%
• Ribonucleoprotein 9%
• Cytochrome C Oxidase 9%
• TOMM20 9%
• Outer Mitochondrial Membrane 9%
• Inner Mitochondrial Membrane 9%
• Beta-Actin 9%
• Sequestosome 1 9%
• Tubulin 9%
• DAPI 9%
• Glyceraldehyde 3-Phosphate Dehydrogenase 9%
• ATG7 9%
• LAMP1 9%
• Mitochondrial Antiviral-Signaling Protein 9%
• ATG12 9%
• Interferon 9%
• Lethal Dose 9%