The next generation of precision medicine: Observational studies, electronic health records, biobanks and continuous monitoring

Benjamin S. Glicksberg, Kipp W. Johnson, Joel T. Dudley

Research output: Contribution to journalReview articlepeer-review

40 Scopus citations

Abstract

Precision medicine can utilize new techniques in order to more effectively translate research findings into clinical practice. In this article, we first explore the limitations of traditional study designs, which stem from (to name a few): massive cost for the assembly of large patient cohorts; non-representative patient data; and the astounding complexity of human biology. Second, we propose that harnessing electronic health records and mobile device biometrics coupled to longitudinal data may prove to be a solution to many of these problems by capturing a 'real world' phenotype. We envision that future biomedical research utilizing more precise approaches to patient care will utilize continuous and longitudinal data sources.

Original languageEnglish
Pages (from-to)R56-R62
JournalHuman Molecular Genetics
Volume27
Issue numberR1
DOIs
StatePublished - 1 May 2018
Externally publishedYes

Fingerprint

Dive into the research topics of 'The next generation of precision medicine: Observational studies, electronic health records, biobanks and continuous monitoring'. Together they form a unique fingerprint.

Cite this