The modulation of immunity by dendritic cells

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


T cell immunity is initiated by specialized antigen presenting cells known as dendritic cells (DCs). Antigen-pulsed DCs have been used to induce anti-tumor T cell and clinical responses in humans, apparently without significant toxicity. Under certain conditions, DCs even silence T cell immune responses in vivo. Therefore, DCs may be valuable tools for modulating immunity in the setting of autoimmunity, cancer, and chronic viral infections.

Original languageEnglish
Pages (from-to)173-182
Number of pages10
JournalClinical and Applied Immunology Reviews
Issue number4-5
StatePublished - Jan 2003
Externally publishedYes


  • Cross-presentation
  • Cytolytic T cells
  • Dentritic cells
  • Helper T cells
  • Immunotherapy


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