The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology

Yvonne J. Huang; Benjamin J. Marsland; Supinda Bunyavanich; Liam O'Mahony; Donald Y.M. Leung; Antonella Muraro; Thomas A. Fleisher

doi:10.1016/j.jaci.2017.02.007

The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology

Yvonne J. Huang, Benjamin J. Marsland, Supinda Bunyavanich, Liam O'Mahony, Donald Y.M. Leung, Antonella Muraro, Thomas A. Fleisher

Research output: Contribution to journal › Article › peer-review

238 Scopus citations

Abstract

PRACTALL is a joint initiative of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology to provide shared evidence-based recommendations on cutting-edge topics in the field of allergy and immunology. PRACTALL 2017 is focused on what has been established regarding the role of the microbiome in patients with asthma, atopic dermatitis, and food allergy. This is complemented by outlining important knowledge gaps regarding its role in allergic disease and delineating strategies necessary to fill these gaps. In addition, a review of progress in approaches used to manipulate the microbiome will be addressed, identifying what has and has not worked to serve as a baseline for future directions to intervene in allergic disease development, progression, or both.

Original language	English
Pages (from-to)	1099-1110
Number of pages	12
Journal	Journal of Allergy and Clinical Immunology
Volume	139
Issue number	4
DOIs	https://doi.org/10.1016/j.jaci.2017.02.007
State	Published - 1 Apr 2017

Keywords

Microbiome
asthma
atopic dermatitis
dysbiosis
food allergy
microbiota
prebiotic
probiotic
systems biology

Access to Document

10.1016/j.jaci.2017.02.007

Fingerprint

Dive into the research topics of 'The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology'. Together they form a unique fingerprint.

Cite this

Huang, Y. J., Marsland, B. J., Bunyavanich, S., O'Mahony, L., Leung, D. Y. M., Muraro, A., & Fleisher, T. A. (2017). The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology. Journal of Allergy and Clinical Immunology, 139(4), 1099-1110. https://doi.org/10.1016/j.jaci.2017.02.007

Huang, Yvonne J. ; Marsland, Benjamin J. ; Bunyavanich, Supinda et al. / The microbiome in allergic disease : Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology. In: Journal of Allergy and Clinical Immunology. 2017 ; Vol. 139, No. 4. pp. 1099-1110.

@article{84d3d4a755204a8e83f18d72271788eb,

title = "The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology",

abstract = "PRACTALL is a joint initiative of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology to provide shared evidence-based recommendations on cutting-edge topics in the field of allergy and immunology. PRACTALL 2017 is focused on what has been established regarding the role of the microbiome in patients with asthma, atopic dermatitis, and food allergy. This is complemented by outlining important knowledge gaps regarding its role in allergic disease and delineating strategies necessary to fill these gaps. In addition, a review of progress in approaches used to manipulate the microbiome will be addressed, identifying what has and has not worked to serve as a baseline for future directions to intervene in allergic disease development, progression, or both.",

keywords = "Microbiome, asthma, atopic dermatitis, dysbiosis, food allergy, microbiota, prebiotic, probiotic, systems biology",

author = "Huang, {Yvonne J.} and Marsland, {Benjamin J.} and Supinda Bunyavanich and Liam O'Mahony and Leung, {Donald Y.M.} and Antonella Muraro and Fleisher, {Thomas A.}",

note = "Publisher Copyright: {\textcopyright} 2017",

year = "2017",

month = apr,

day = "1",

doi = "10.1016/j.jaci.2017.02.007",

language = "English",

volume = "139",

pages = "1099--1110",

journal = "Journal of Allergy and Clinical Immunology",

issn = "0091-6749",

publisher = "Mosby Inc.",

number = "4",

}

Huang, YJ, Marsland, BJ, Bunyavanich, S, O'Mahony, L, Leung, DYM, Muraro, A & Fleisher, TA 2017, 'The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology', Journal of Allergy and Clinical Immunology, vol. 139, no. 4, pp. 1099-1110. https://doi.org/10.1016/j.jaci.2017.02.007

The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology. / Huang, Yvonne J.; Marsland, Benjamin J.; Bunyavanich, Supinda et al.
In: Journal of Allergy and Clinical Immunology, Vol. 139, No. 4, 01.04.2017, p. 1099-1110.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - The microbiome in allergic disease

T2 - Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology

AU - Huang, Yvonne J.

AU - Marsland, Benjamin J.

AU - Bunyavanich, Supinda

AU - O'Mahony, Liam

AU - Leung, Donald Y.M.

AU - Muraro, Antonella

AU - Fleisher, Thomas A.

PY - 2017/4/1

Y1 - 2017/4/1

N2 - PRACTALL is a joint initiative of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology to provide shared evidence-based recommendations on cutting-edge topics in the field of allergy and immunology. PRACTALL 2017 is focused on what has been established regarding the role of the microbiome in patients with asthma, atopic dermatitis, and food allergy. This is complemented by outlining important knowledge gaps regarding its role in allergic disease and delineating strategies necessary to fill these gaps. In addition, a review of progress in approaches used to manipulate the microbiome will be addressed, identifying what has and has not worked to serve as a baseline for future directions to intervene in allergic disease development, progression, or both.

AB - PRACTALL is a joint initiative of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology to provide shared evidence-based recommendations on cutting-edge topics in the field of allergy and immunology. PRACTALL 2017 is focused on what has been established regarding the role of the microbiome in patients with asthma, atopic dermatitis, and food allergy. This is complemented by outlining important knowledge gaps regarding its role in allergic disease and delineating strategies necessary to fill these gaps. In addition, a review of progress in approaches used to manipulate the microbiome will be addressed, identifying what has and has not worked to serve as a baseline for future directions to intervene in allergic disease development, progression, or both.

KW - Microbiome

KW - asthma

KW - atopic dermatitis

KW - dysbiosis

KW - food allergy

KW - microbiota

KW - prebiotic

KW - probiotic

KW - systems biology

UR - http://www.scopus.com/inward/record.url?scp=85017298186&partnerID=8YFLogxK

U2 - 10.1016/j.jaci.2017.02.007

DO - 10.1016/j.jaci.2017.02.007

M3 - Article

C2 - 28257972

AN - SCOPUS:85017298186

SN - 0091-6749

VL - 139

SP - 1099

EP - 1110

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 4

ER -

Huang YJ, Marsland BJ, Bunyavanich S, O'Mahony L, Leung DYM, Muraro A et al. The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology. Journal of Allergy and Clinical Immunology. 2017 Apr 1;139(4):1099-1110. doi: 10.1016/j.jaci.2017.02.007