The Long-Term Management of Ovarian Cancer

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

This chapter highlights the approach to long-term care of patients with epithelial ovarian cancer. Epithelial ovarian cancer includes wide spectrum of disease from early stage tumor to very aggressive disease presented in advanced stage with rapid progression and not amenable to any intervention. The aggressive treatment of epithelial ovarian cancer has shown remarkable improvements in the response rates of patients with advanced ovarian cancer. Most women diagnosed with ovarian cancer in advanced stage have this disease beyond the ovaries and are not curable by surgical extirpation alone. Adjuvant cytotoxic therapy is useful in both early and advanced optimally cytoreduced ovarian cancer. The most important advance in treatment of ovarian cancer is the development of chemotherapeutic regimens based on platinum coordination compounds. Long-term follow up of patients with ovarian cancer shows that response to cytotoxic treatment with platinum is a predictor of survival, with 23% decrease in the relative death rate compared to those who did not receive platinum..

Original languageEnglish
Title of host publicationDiagnosis and Management of Ovarian Disorders, Second Edition
PublisherElsevier
Pages467-476
Number of pages10
ISBN (Electronic)9780120536429
DOIs
StatePublished - 1 Jan 2003

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