The landscape of rare genetic variation associated with inflammatory bowel disease and Parkinson’s disease comorbidity

Biochemistry, Genetics and Molecular Biology

• Genetic Divergence 100%
• Genetic Variation 100%
• LRRK2 100%
• Comorbidity 100%
• Genetics 40%
• Candidate Gene 40%
• Autophagy 40%
• Missense 40%
• Exome 40%
• Relatedness 40%
• Genetic Determinism 20%
• Interleukin-1 20%
• Gene Cluster 20%
• MAPK Signaling 20%
• Rare Variant 20%

Keyphrases

• Parkinson's Disease 100%
• Inflammatory Bowel Disease 100%
• Rare Genetic Variation 100%
• Disease Comorbidity 100%
• Leucine-rich Repeat Kinase 2 (LRRK2) 26%
• Missense Variants 10%
• Significant Genes 10%
• UK Biobank 10%
• Disease Genes 10%
• Biobank 10%
• Enriched Pathways 10%
• Whole Exome 10%
• Network Applications 10%
• Phenome-wide Association Study (PheWAS) 10%
• Sequence Kernel Association Test 10%
• Biological Relatedness 10%
• Inflammation 5%
• Pathophysiological Processes 5%
• Comorbidity 5%
• Therapeutic Intervention 5%
• Autophagy 5%
• Interleukin-1β 5%
• Potential Contributor 5%
• Enrichment Analysis 5%
• Rare Variants 5%
• Rare Genetic Variants 5%
• Protein-protein Interaction Network 5%
• Disease Pathogenesis 5%
• Systemic Inflammation 5%
• Gene Cluster 5%
• Inflammatory Genes 5%
• Autophagy-related Genes 5%
• Genetic Basis 5%
• Clustering Analysis 5%
• Biological Significance 5%
• Pathway Enrichment 5%
• Gene Set 5%
• Disease Groups 5%
• Whole Genome 5%
• Biologically Relevant 5%
• MAPK Signaling 5%
• Shared Genetics 5%
• Provided Support 5%
• Chronic Disorders 5%
• IL10RA 5%
• G2019S 5%
• Parkinson's Disease Risk 5%
• Interaction Pathway 5%
• European Patients 5%
• Novel Candidate Genes 5%
• Association Network 5%
• NAD Signaling 5%
• Ontology Enrichment 5%