The in vitro metabolism of hainanensine derivative HH07A by rat liver microsomes

W. J. Zhang; T. H. Zhou; Y. Y. Cui

The in vitro metabolism of hainanensine derivative HH07A by rat liver microsomes

W. J. Zhang
, T. H. Zhou
, Y. Y. Cui

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The metabolism of hainanensine derivative HH07A has been studied in vitro with rat microsomes. A method of HPLC-DAD was developed for screening the metabolites from the microsomal incubation system. Two metabolites were found according to their UV spectra. One of them was extracted and purified with preparative HPLC and TLC, its chemical structure was identified by UV, IR, MS and NMR.

Original language	English
Pages (from-to)	116-120
Number of pages	5
Journal	Yaoxue Xuebao
Volume	32
Issue number	2
State	Published - Feb 1997
Externally published	Yes

Keywords

HPLC
Hainanensine derivative HH07A
Metabolism in vitro

Cite this

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title = "The in vitro metabolism of hainanensine derivative HH07A by rat liver microsomes",

abstract = "The metabolism of hainanensine derivative HH07A has been studied in vitro with rat microsomes. A method of HPLC-DAD was developed for screening the metabolites from the microsomal incubation system. Two metabolites were found according to their UV spectra. One of them was extracted and purified with preparative HPLC and TLC, its chemical structure was identified by UV, IR, MS and NMR.",

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author = "Zhang, \{W. J.\} and Zhou, \{T. H.\} and Cui, \{Y. Y.\}",

year = "1997",

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journal = "Yaoxue Xuebao",

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AU - Zhang, W. J.

AU - Zhou, T. H.

AU - Cui, Y. Y.

PY - 1997/2

Y1 - 1997/2

N2 - The metabolism of hainanensine derivative HH07A has been studied in vitro with rat microsomes. A method of HPLC-DAD was developed for screening the metabolites from the microsomal incubation system. Two metabolites were found according to their UV spectra. One of them was extracted and purified with preparative HPLC and TLC, its chemical structure was identified by UV, IR, MS and NMR.

AB - The metabolism of hainanensine derivative HH07A has been studied in vitro with rat microsomes. A method of HPLC-DAD was developed for screening the metabolites from the microsomal incubation system. Two metabolites were found according to their UV spectra. One of them was extracted and purified with preparative HPLC and TLC, its chemical structure was identified by UV, IR, MS and NMR.

KW - HPLC

KW - Hainanensine derivative HH07A

KW - Metabolism in vitro

UR - https://www.scopus.com/pages/publications/0031290815

M3 - Article

C2 - 11243194

AN - SCOPUS:0031290815

SN - 0513-4870

VL - 32

SP - 116

EP - 120

JO - Yaoxue Xuebao

JF - Yaoxue Xuebao

IS - 2

ER -

The in vitro metabolism of hainanensine derivative HH07A by rat liver microsomes

Abstract

Keywords

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