The impact of ulcerative colitis on patients' lives compared to other chronic diseases: A patient survey

  • David T. Rubin
  • , Marla C. Dubinsky
  • , Remo Panaccione
  • , Corey A. Siegel
  • , David G. Binion
  • , Sunanda V. Kane
  • , Joseph Hopper

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

Purpose: This study was designed to identify the impact chronic ulcerative colitis (UC) has on the lives of patients compared to other chronic conditions. Overall, 451 patients with UC, 309 with rheumatoid arthritis, 305 with asthma, and 305 with migraine headaches were recruited in an Internet survey designed to assess a variety of disease-impact indices. Results: Patients with UC reported a mean of eight (self-defined) flare-ups in the previous 12 months. Significantly more patients with UC (81%) believed that the quantity of flare-ups they experienced was 'normal', compared to patients with migraine headaches (64%) or asthma (75%). Patients with UC also reported significantly more worry about disease complications (84%), depression (62%), and embarrassment (70%) than patients with the other chronic conditions. Conclusions: Compared to patients with other chronic conditions, patients with UC perceive substantially more negative impact upon their lives, especially with regard to the psychological burden.

Original languageEnglish
Pages (from-to)1044-1052
Number of pages9
JournalDigestive Diseases and Sciences
Volume55
Issue number4
DOIs
StatePublished - Apr 2010
Externally publishedYes

Keywords

  • Chronic disease
  • Disease burden
  • Quality of life
  • Ulcerative colitis

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