TY - JOUR
T1 - The impact of level of injury on patterns of cognitive dysfunction in individuals with spinal cord injury
AU - Chiaravalloti, Nancy D.
AU - Weber, Erica
AU - Wylie, Glenn
AU - Dyson-Hudson, Trevor
AU - Wecht, Jill M.
N1 - Funding Information:
Contributors None. Funding This work was supported by the New Jersey Commission on Spinal Cord Research [grant number CSCR13IRG018], the Rehabilitation Research and Development Service [grant number B9212-C & B2020-C] and the National Institute on Disability, Independent Living, and Rehabilitation Research [NIDILRR grant number 90SI5026]. Conflicts of interest None.
Publisher Copyright:
© The Academy of Spinal Cord Injury Professionals, Inc. 2019.
PY - 2020/9/2
Y1 - 2020/9/2
N2 - Context: While it is well recognized that physical and physiological changes are more prominent in individuals with higher neurologic levels of spinal cord injury (SCI), the impact of level of lesion on cognition is less clear. Design: Cross-sectional, 3-group. Setting: Non-profit rehabilitation research foundation. Participants: 59 individuals with SCI (30 with tetraplegia, 29 with paraplegia) and 30 age-matched healthy controls (HC). Interventions: None. Outcome Measures: Neuropsychological tests in the domains of attention, working memory, processing speed, executive control, and learning and memory. Results: Results indicated significantly lower test performance in individuals with paraplegia on new learning and memory testing compared to HC. In contrast, compared to HC the group with tetraplegia, showed a significantly impaired performance on a processing speed task, and both the tetraplegia and the paraplegia groups were similarly impaired on a verbal fluency measure. SCI groups did not differ on any cognitive measure. Conclusion: Individuals with SCI may display different patterns of cognitive performance based on their level of injury.
AB - Context: While it is well recognized that physical and physiological changes are more prominent in individuals with higher neurologic levels of spinal cord injury (SCI), the impact of level of lesion on cognition is less clear. Design: Cross-sectional, 3-group. Setting: Non-profit rehabilitation research foundation. Participants: 59 individuals with SCI (30 with tetraplegia, 29 with paraplegia) and 30 age-matched healthy controls (HC). Interventions: None. Outcome Measures: Neuropsychological tests in the domains of attention, working memory, processing speed, executive control, and learning and memory. Results: Results indicated significantly lower test performance in individuals with paraplegia on new learning and memory testing compared to HC. In contrast, compared to HC the group with tetraplegia, showed a significantly impaired performance on a processing speed task, and both the tetraplegia and the paraplegia groups were similarly impaired on a verbal fluency measure. SCI groups did not differ on any cognitive measure. Conclusion: Individuals with SCI may display different patterns of cognitive performance based on their level of injury.
KW - Cognitive deficits
KW - Executive functioning
KW - Memory
KW - Processing speed
KW - Spinal cord injury
UR - http://www.scopus.com/inward/record.url?scp=85076877398&partnerID=8YFLogxK
U2 - 10.1080/10790268.2019.1696076
DO - 10.1080/10790268.2019.1696076
M3 - Article
C2 - 31859606
AN - SCOPUS:85076877398
VL - 43
SP - 633
EP - 641
JO - Journal of Spinal Cord Medicine
JF - Journal of Spinal Cord Medicine
SN - 1079-0268
IS - 5
ER -