The impact of adhesions on operations and postoperative recovery in colon cancer surgery

Ramzi Amri; Hannah C. Den Boon; Liliana G. Bordeianou; Patricia Sylla; David L. Berger

doi:10.1016/j.amjsurg.2013.01.018

The impact of adhesions on operations and postoperative recovery in colon cancer surgery

Ramzi Amri
, Hannah C. Den Boon
, Liliana G. Bordeianou
, Patricia Sylla
, David L. Berger

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Background: Many surgeons assume that adhesions encountered during surgery negatively influence surgical outcomes. This article attempts to assess the role adhesions have on outcomes of colon cancer surgery. Methods: Records of 1,071 consecutive patients operated for colonic adenocarcinoma (2004-2011) were reviewed. Patients were assigned to 3 groups: no adhesions, any adhesions, or dense adhesions. Multivariate regression assessed the association between adhesions and the duration of surgery and stay as well as laparoscopic conversion and complication rates. Results: Adhesions were encountered in 329 (30.7%) patients; 138 (12.8%) had dense adhesions. After correction for age and comorbidities, having adhesions was associated with longer surgeries (P <.001), longer hospital stays (P =.029), a borderline significantly higher conversion rate (P =.058), and a delayed return of bowel function (P =.037). Dense adhesions had stronger associations with surgical duration (P <.001), stay duration (P <.001), and conversion (P <.001). Conclusions: Abdominal adhesions independently put patients at risk for a longer and more complicated perioperative stay after colon cancer surgery.

Original language	English
Pages (from-to)	166-171
Number of pages	6
Journal	American Journal of Surgery
Volume	206
Issue number	2
DOIs	https://doi.org/10.1016/j.amjsurg.2013.01.018
State	Published - Aug 2013
Externally published	Yes

Keywords

Colon cancer
Complications
Intra-abdominal adhesions
Stay duration
Surgery duration

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10.1016/j.amjsurg.2013.01.018

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@article{b25c1d67c8a9434f97d9b62b4fafaef6,

title = "The impact of adhesions on operations and postoperative recovery in colon cancer surgery",

abstract = "Background: Many surgeons assume that adhesions encountered during surgery negatively influence surgical outcomes. This article attempts to assess the role adhesions have on outcomes of colon cancer surgery. Methods: Records of 1,071 consecutive patients operated for colonic adenocarcinoma (2004-2011) were reviewed. Patients were assigned to 3 groups: no adhesions, any adhesions, or dense adhesions. Multivariate regression assessed the association between adhesions and the duration of surgery and stay as well as laparoscopic conversion and complication rates. Results: Adhesions were encountered in 329 (30.7\%) patients; 138 (12.8\%) had dense adhesions. After correction for age and comorbidities, having adhesions was associated with longer surgeries (P <.001), longer hospital stays (P =.029), a borderline significantly higher conversion rate (P =.058), and a delayed return of bowel function (P =.037). Dense adhesions had stronger associations with surgical duration (P <.001), stay duration (P <.001), and conversion (P <.001). Conclusions: Abdominal adhesions independently put patients at risk for a longer and more complicated perioperative stay after colon cancer surgery.",

keywords = "Colon cancer, Complications, Intra-abdominal adhesions, Stay duration, Surgery duration",

author = "Ramzi Amri and \{Den Boon\}, \{Hannah C.\} and Bordeianou, \{Liliana G.\} and Patricia Sylla and Berger, \{David L.\}",

note = "Funding Information: Supported by the Harvard Catalyst/The Harvard Clinical and Translational Science Center (National Center for Research Resources and the National Center for Advancing Translational Sciences , National Institutes of Health Award 8UL1TR000170-05, and financial contributions from Harvard University and its affiliated academic health care centers) and the Dutch Cancer Society, the Dutch Digestive Society, the Amsterdam University Funds, and the Fulbright Foundation. ",

year = "2013",

month = aug,

doi = "10.1016/j.amjsurg.2013.01.018",

language = "English",

volume = "206",

pages = "166--171",

journal = "American Journal of Surgery",

issn = "0002-9610",

publisher = "Elsevier Inc.",

number = "2",

}

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T1 - The impact of adhesions on operations and postoperative recovery in colon cancer surgery

AU - Amri, Ramzi

AU - Den Boon, Hannah C.

AU - Bordeianou, Liliana G.

AU - Sylla, Patricia

AU - Berger, David L.

N1 - Funding Information: Supported by the Harvard Catalyst/The Harvard Clinical and Translational Science Center (National Center for Research Resources and the National Center for Advancing Translational Sciences , National Institutes of Health Award 8UL1TR000170-05, and financial contributions from Harvard University and its affiliated academic health care centers) and the Dutch Cancer Society, the Dutch Digestive Society, the Amsterdam University Funds, and the Fulbright Foundation.

PY - 2013/8

Y1 - 2013/8

N2 - Background: Many surgeons assume that adhesions encountered during surgery negatively influence surgical outcomes. This article attempts to assess the role adhesions have on outcomes of colon cancer surgery. Methods: Records of 1,071 consecutive patients operated for colonic adenocarcinoma (2004-2011) were reviewed. Patients were assigned to 3 groups: no adhesions, any adhesions, or dense adhesions. Multivariate regression assessed the association between adhesions and the duration of surgery and stay as well as laparoscopic conversion and complication rates. Results: Adhesions were encountered in 329 (30.7%) patients; 138 (12.8%) had dense adhesions. After correction for age and comorbidities, having adhesions was associated with longer surgeries (P <.001), longer hospital stays (P =.029), a borderline significantly higher conversion rate (P =.058), and a delayed return of bowel function (P =.037). Dense adhesions had stronger associations with surgical duration (P <.001), stay duration (P <.001), and conversion (P <.001). Conclusions: Abdominal adhesions independently put patients at risk for a longer and more complicated perioperative stay after colon cancer surgery.

AB - Background: Many surgeons assume that adhesions encountered during surgery negatively influence surgical outcomes. This article attempts to assess the role adhesions have on outcomes of colon cancer surgery. Methods: Records of 1,071 consecutive patients operated for colonic adenocarcinoma (2004-2011) were reviewed. Patients were assigned to 3 groups: no adhesions, any adhesions, or dense adhesions. Multivariate regression assessed the association between adhesions and the duration of surgery and stay as well as laparoscopic conversion and complication rates. Results: Adhesions were encountered in 329 (30.7%) patients; 138 (12.8%) had dense adhesions. After correction for age and comorbidities, having adhesions was associated with longer surgeries (P <.001), longer hospital stays (P =.029), a borderline significantly higher conversion rate (P =.058), and a delayed return of bowel function (P =.037). Dense adhesions had stronger associations with surgical duration (P <.001), stay duration (P <.001), and conversion (P <.001). Conclusions: Abdominal adhesions independently put patients at risk for a longer and more complicated perioperative stay after colon cancer surgery.

KW - Colon cancer

KW - Complications

KW - Intra-abdominal adhesions

KW - Stay duration

KW - Surgery duration

UR - https://www.scopus.com/pages/publications/84880573358

U2 - 10.1016/j.amjsurg.2013.01.018

DO - 10.1016/j.amjsurg.2013.01.018

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EP - 171

JO - American Journal of Surgery

JF - American Journal of Surgery

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ER -

The impact of adhesions on operations and postoperative recovery in colon cancer surgery

Abstract

Keywords

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