TY - JOUR
T1 - The idiopathic hyperkinetic heart syndrome
T2 - clinical course and long-term prognosis
AU - Gillum, Richard F.
AU - Teichholz, Louis E.
AU - Herman, Michael V.
AU - Gorlin, Richard
N1 - Funding Information:
From the Cardiova~ular Division, Department of Medicine, Peter Bent Brigham Hospital; and the Department of Medicine, Harvard Medical School. Supported by United States Public Health Service Grants HLO56079 and HL11306. Received for publication March 9, 1981; revision received May 6, 1981; accepted June 2, 1981. Reprint requests: Richard F. Gillum, M.D., University Beacon Street, SE, Minneapolis, MN 55465.
PY - 1981/10
Y1 - 1981/10
N2 - Nineteen of the originally reported 24 patients having the idiopathic hyperkinetic heart syndrome were followed for periods of 11 to 25 years. One patient died of complicating severe mitral stenosis. Of the remaining 18 patients, nine had complete physical examinations and ECG records. Only one of these patients was symptomatic at the time of reexamination. Murmurs originally present in eight of nine patients were present in only five of nine at reexamination; hyperkinetic circulation and heart, originally present in eight, were found in only two at follow-up; and systolic hypertension, present in seven at beginning of the study, was only present in four at follow-up. ECG abnormalities (usually left ventricular hypertrophy) regressed in the majority. Persistent elevation of cardiac index and systolic ejection rate were found at repeat catheterization in the single symptomatic patient who had congestive cardiomyopathy. Uncomplicated idiopathic hyperkinetic heart syndrome appears to have an excellent long-term prognosis.
AB - Nineteen of the originally reported 24 patients having the idiopathic hyperkinetic heart syndrome were followed for periods of 11 to 25 years. One patient died of complicating severe mitral stenosis. Of the remaining 18 patients, nine had complete physical examinations and ECG records. Only one of these patients was symptomatic at the time of reexamination. Murmurs originally present in eight of nine patients were present in only five of nine at reexamination; hyperkinetic circulation and heart, originally present in eight, were found in only two at follow-up; and systolic hypertension, present in seven at beginning of the study, was only present in four at follow-up. ECG abnormalities (usually left ventricular hypertrophy) regressed in the majority. Persistent elevation of cardiac index and systolic ejection rate were found at repeat catheterization in the single symptomatic patient who had congestive cardiomyopathy. Uncomplicated idiopathic hyperkinetic heart syndrome appears to have an excellent long-term prognosis.
UR - https://www.scopus.com/pages/publications/0019478819
U2 - 10.1016/0002-8703(81)90098-3
DO - 10.1016/0002-8703(81)90098-3
M3 - Article
C2 - 7282518
AN - SCOPUS:0019478819
SN - 0002-8703
VL - 102
SP - 728
EP - 734
JO - American Heart Journal
JF - American Heart Journal
IS - 4
ER -