The G₂ DNA damage checkpoint: Could this ancient regulator be the achilles heel of cancer?

Keyphrases

• DNA Damage 100%
• Checkpoint Kinase 1 (CHK1) 100%
• DNA Damage Checkpoint 100%
• Achilles Heel 100%
• G2 Checkpoint 100%
• In Cancer 50%
• Cancer Cells 50%
• Mitosis 50%
• Tumor Cells 50%
• Signaling Pathway 50%
• Serine-threonine Kinase 50%
• Human Biology 50%
• Cancer Therapy 50%
• Cancer Prevention 50%
• Tumor Protein p53 (TP53) 50%
• Cell Growth 50%
• Anticancer Drugs 50%
• Cell Cycle Stages 50%
• Tumor Cell Viability 50%
• Daughter Cells 50%
• Growth Development 50%
• Genome Integrity 50%
• Checkpoint Genes 50%
• Fission Yeast Schizosaccharomyces Pombe 50%
• Organismal Development 50%
• Checkpoint Response 50%
• Fission Yeast 50%
• Cell Cycle Checkpoint 50%
• Concerted Action 50%

Biochemistry, Genetics and Molecular Biology

• P53 100%
• DNA Damage Checkpoint 100%
• G2 Phase Cell Cycle Checkpoint 100%
• Fission Yeast 100%
• Cancer Cell 50%
• Cell Viability 50%
• Kinase 50%
• Phosphotransferase 50%
• Cell Cycle 50%
• DNA Repair 50%
• Signal Transduction 50%
• Threonine 50%
• Serine 50%
• Tumor Suppressor Protein 50%
• DNA Damage 50%
• Cell Growth 50%
• Daughter Cell 50%
• Schizosaccharomyces Pombe 50%
• Cell Cycle Checkpoint 50%