Abstract
Advancements in molecular technology coupled with a greater awareness of the human genome and epigenome have broadened our understanding of the genetic contributions to the diabetic pregnancy. There are multiple genes and pathways that can result in a hyperglycemic environment for the fetus. Exposure to this environment in utero has an impact on the risk of adult-onset chronic diseases. How identification of an individual's genetic variants will impact clinical care and outcomes will continue to evolve as our understanding grows.
Original language | English |
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Article number | 1417 |
Pages (from-to) | 102-109 |
Number of pages | 8 |
Journal | Best Practice and Research: Clinical Obstetrics and Gynaecology |
Volume | 29 |
Issue number | 1 |
DOIs | |
State | Published - 1 Jan 2015 |
Externally published | Yes |
Keywords
- diabetes
- epigenomics
- genetics
- pregnancy