The frequency of chromosome aberrations in tall men with special reference to 47,XYY and 47,XXY

J. Philip, C. Lundsteen, D. Owen, K. Hirschhorn

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

All men born during the years 1944-1947 to mothers who were inhabitants of Copenhagen when they gave birth, were identified. The adult heights of all but 2,552 of these 31,438 men were obtained; a group of 4,591 men at least 184 cm tall were selected for examination. Samples for chromosome studies were obtained from 4,139 (90.2%) of these tall men. A total of 41 (1%) abnormalities were identified (33 sex chromosome abnormalities, including 12 XYYs (0.3%) and 16 XXYs (0.4%), 6 autosomal abnormalities, and two of uncertain origin). The XYY and XXY groups were taller than the selected sample of tall XY men.

Original languageEnglish
Pages (from-to)404-411
Number of pages8
JournalAmerican Journal of Human Genetics
Volume28
Issue number4
StatePublished - 1976
Externally publishedYes

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