The formation of a stable complex between dissociated proteoglycan and hyaluronic acid in the absence of a link protein

D. A. Swann; S. Powell; J. Broadhurst; E. Sordillo; S. Sotman

doi:10.1042/bj1570503

The formation of a stable complex between dissociated proteoglycan and hyaluronic acid in the absence of a link protein

D. A. Swann
, S. Powell
, J. Broadhurst
, E. Sordillo
, S. Sotman

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

A proteoglycan fraction prepared from bovine articular cartilage under dissociative conditions was shown to interact with three purified hyaluronic acid preparations to form stable complexes in the analytical ultracentrifuge. It is concluded from these experiments that, although link proteins are associated with hyaluronic acid and proteoglycans in cartilage extracts, they are not an essential requirement for the formation of stable complexes between these macromolecular constituents.

Original language	English
Pages (from-to)	503-506
Number of pages	4
Journal	Biochemical Journal
Volume	157
Issue number	2
DOIs	https://doi.org/10.1042/bj1570503
State	Published - 1976

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title = "The formation of a stable complex between dissociated proteoglycan and hyaluronic acid in the absence of a link protein",

abstract = "A proteoglycan fraction prepared from bovine articular cartilage under dissociative conditions was shown to interact with three purified hyaluronic acid preparations to form stable complexes in the analytical ultracentrifuge. It is concluded from these experiments that, although link proteins are associated with hyaluronic acid and proteoglycans in cartilage extracts, they are not an essential requirement for the formation of stable complexes between these macromolecular constituents.",

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T1 - The formation of a stable complex between dissociated proteoglycan and hyaluronic acid in the absence of a link protein

AU - Swann, D. A.

AU - Powell, S.

AU - Broadhurst, J.

AU - Sordillo, E.

AU - Sotman, S.

PY - 1976

Y1 - 1976

N2 - A proteoglycan fraction prepared from bovine articular cartilage under dissociative conditions was shown to interact with three purified hyaluronic acid preparations to form stable complexes in the analytical ultracentrifuge. It is concluded from these experiments that, although link proteins are associated with hyaluronic acid and proteoglycans in cartilage extracts, they are not an essential requirement for the formation of stable complexes between these macromolecular constituents.

AB - A proteoglycan fraction prepared from bovine articular cartilage under dissociative conditions was shown to interact with three purified hyaluronic acid preparations to form stable complexes in the analytical ultracentrifuge. It is concluded from these experiments that, although link proteins are associated with hyaluronic acid and proteoglycans in cartilage extracts, they are not an essential requirement for the formation of stable complexes between these macromolecular constituents.

UR - https://www.scopus.com/pages/publications/0017159927

U2 - 10.1042/bj1570503

DO - 10.1042/bj1570503

M3 - Article

AN - SCOPUS:0017159927

SN - 0264-6021

VL - 157

SP - 503

EP - 506

JO - Biochemical Journal

JF - Biochemical Journal

IS - 2

ER -

The formation of a stable complex between dissociated proteoglycan and hyaluronic acid in the absence of a link protein

Abstract

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