The formation of a stable complex between dissociated proteoglycan and hyaluronic acid in the absence of a link protein

D. A. Swann, S. Powell, J. Broadhurst, E. Sordillo, S. Sotman

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

A proteoglycan fraction prepared from bovine articular cartilage under dissociative conditions was shown to interact with three purified hyaluronic acid preparations to form stable complexes in the analytical ultracentrifuge. It is concluded from these experiments that, although link proteins are associated with hyaluronic acid and proteoglycans in cartilage extracts, they are not an essential requirement for the formation of stable complexes between these macromolecular constituents.

Original languageEnglish
Pages (from-to)503-506
Number of pages4
JournalUnknown Journal
Volume157
Issue number2
DOIs
StatePublished - 1976

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