The extracellular matrix (ECM) serves as a microenvironmental niche providing both biophysical and biochemical signals in which cells reside and function within the body. Therefore, understanding the composition, structure, and functions of the native ECM is essential to engineering biomaterials for maintaining and/or directing cellular function for biomedical applications. This chapter summarizes compositions, properties, and functions of the native ECM, and how these inform the understanding and engineering of cell–biomaterial interactions. The following concepts are covered:1. Definition, properties, and functions of the ECM2. Cell–biomaterial interactions.
|Title of host publication||Biomaterials Science|
|Subtitle of host publication||An Introduction to Materials in Medicine|
|Number of pages||15|
|State||Published - 1 Jan 2020|
- Extracellular matrix
- Stem cells
- Tissue Constituents