The Evolving and Multidisciplinary Considerations in Nodal Radiation in Breast Cancer

Naamit K. Gerber; Elisa Port; Manjeet Chadha

doi:10.1016/j.semradonc.2018.11.008

The Evolving and Multidisciplinary Considerations in Nodal Radiation in Breast Cancer

Naamit K. Gerber, Elisa Port, Manjeet Chadha

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

The therapeutic management of regional lymph nodes in breast cancer has seen a remarkable change in the past 2 decades. Clinical trials have refined our knowledge regarding the biology of the disease including the prognostic significance of disease in the regional lymph nodes. The contemporary management of lymph nodes is also influenced by advances in surgical technique, radiation oncology delivery systems, and effective systemic therapy regimens. This paper describes the role of regional nodal irradiation in the context of the de-escalation of axillary surgery, improved understanding of the molecular and pathologic features, and increasing use of neoadjuvant chemotherapy.

Original language	English
Pages (from-to)	150-157
Number of pages	8
Journal	Seminars in Radiation Oncology
Volume	29
Issue number	2
DOIs	https://doi.org/10.1016/j.semradonc.2018.11.008
State	Published - Apr 2019
Externally published	Yes

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title = "The Evolving and Multidisciplinary Considerations in Nodal Radiation in Breast Cancer",

abstract = "The therapeutic management of regional lymph nodes in breast cancer has seen a remarkable change in the past 2 decades. Clinical trials have refined our knowledge regarding the biology of the disease including the prognostic significance of disease in the regional lymph nodes. The contemporary management of lymph nodes is also influenced by advances in surgical technique, radiation oncology delivery systems, and effective systemic therapy regimens. This paper describes the role of regional nodal irradiation in the context of the de-escalation of axillary surgery, improved understanding of the molecular and pathologic features, and increasing use of neoadjuvant chemotherapy.",

author = "Gerber, {Naamit K.} and Elisa Port and Manjeet Chadha",

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AU - Port, Elisa

AU - Chadha, Manjeet

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N2 - The therapeutic management of regional lymph nodes in breast cancer has seen a remarkable change in the past 2 decades. Clinical trials have refined our knowledge regarding the biology of the disease including the prognostic significance of disease in the regional lymph nodes. The contemporary management of lymph nodes is also influenced by advances in surgical technique, radiation oncology delivery systems, and effective systemic therapy regimens. This paper describes the role of regional nodal irradiation in the context of the de-escalation of axillary surgery, improved understanding of the molecular and pathologic features, and increasing use of neoadjuvant chemotherapy.

AB - The therapeutic management of regional lymph nodes in breast cancer has seen a remarkable change in the past 2 decades. Clinical trials have refined our knowledge regarding the biology of the disease including the prognostic significance of disease in the regional lymph nodes. The contemporary management of lymph nodes is also influenced by advances in surgical technique, radiation oncology delivery systems, and effective systemic therapy regimens. This paper describes the role of regional nodal irradiation in the context of the de-escalation of axillary surgery, improved understanding of the molecular and pathologic features, and increasing use of neoadjuvant chemotherapy.

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The Evolving and Multidisciplinary Considerations in Nodal Radiation in Breast Cancer

Abstract

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