TY - JOUR
T1 - The Evolutionary Origin of Extracellular Chemical Messengers
AU - Sandor, Thomas
AU - Mehdi, Afzal Z.
AU - Pearse, Anthony G.E.
AU - Taylor, Lawrence H.
AU - Adelson, Joel W.
AU - Roth, Jesse
AU - Leroith, Derek
AU - Shiloach, Joseph
AU - Rosenzweig, James L.
AU - Lesniak, Maxine A.
AU - Havrankova, Jana
PY - 1982/9/2
Y1 - 1982/9/2
N2 - To the Editor: We congratulate Roth and his colleagues for their excellent work (March 4 issue).1 However, we would like to point out that some years ago, we proposed an almost identical theory for the original nature and evolution of hormones, although in contrast to Roth and his group, we have concentrated on steroidal messengers. Hormonal steroids were first isolated from mammalian adrenals and gonads. By the early 1970s, the idea of their exclusively mammalian or vertebrate role had been successfully challenged.2 The omnipresence of vertebrate-type hormonal steroids is now generally accepted, and we have documented the general occurrence or.
AB - To the Editor: We congratulate Roth and his colleagues for their excellent work (March 4 issue).1 However, we would like to point out that some years ago, we proposed an almost identical theory for the original nature and evolution of hormones, although in contrast to Roth and his group, we have concentrated on steroidal messengers. Hormonal steroids were first isolated from mammalian adrenals and gonads. By the early 1970s, the idea of their exclusively mammalian or vertebrate role had been successfully challenged.2 The omnipresence of vertebrate-type hormonal steroids is now generally accepted, and we have documented the general occurrence or.
UR - http://www.scopus.com/inward/record.url?scp=0020473647&partnerID=8YFLogxK
U2 - 10.1056/NEJM198209023071018
DO - 10.1056/NEJM198209023071018
M3 - Letter
C2 - 6125885
AN - SCOPUS:0020473647
SN - 0028-4793
VL - 307
SP - 629
EP - 631
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 10
ER -