The evolution of neuron types and cortical histology in apes and humans

C. C. Sherwood, P. R. Hof

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

32 Scopus citations


This article reviews the comparative anatomy of cortical architecture in apes and humans. While relatively few modern studies have investigated the ape cortex, evidence indicates that several important changes to cortical histological structure have occurred along the hominoid lineage. Given that phylogenetic variation has been revealed across widespread regions, including primary visual cortex, anterior cingulate cortex, and prefrontal cortex, it appears that many different functional systems have been modified during the evolution of these species.

Original languageEnglish
Title of host publicationPrimates
PublisherElsevier Inc.
Number of pages24
ISBN (Print)9780123708786
StatePublished - 2007


  • Ape
  • Bonobo
  • Brain evolution
  • Calcium-binding proteins
  • Cerebral cortex
  • Chemoarchitecture
  • Chimpanzee
  • Cytoarchitecture
  • Gibbon
  • Gorilla
  • Hominoid
  • Human
  • Neurofilament protein
  • Orangutan
  • Primate


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