Abstract
Diabetic ketoacidosis (DKA) is a common, serious acute complication in children with diabetes mellitus (DM). DKA can accompany new-onset type 1 insulin-dependent DM, or it can occur with established type 1 DM, during the increased demands of an acute illness or with decreased insulin delivery due to omitted doses or insulin pump failure. In addition, DKA episodes in children with type 2 DM are being reported with greater frequency. Although the diagnosis is usually straightforward in a known diabetes patient with expected findings, a sizable proportion of patients with new-onset DM present with DKA. The purpose of this comprehensive review is to acquaint clinicians with details regarding the pathophysiology, treatment caveats, and potential complications of DKA.
| Original language | English |
|---|---|
| Pages (from-to) | 551-564 |
| Number of pages | 14 |
| Journal | Clinical Pediatrics |
| Volume | 62 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 2023 |
Keywords
- cerebral edema
- diabetes
- hyperglycemia
- insulin
- ketoacidosis