The Einstein Center for Epigenomics: Studying the role of epigenomic dysregulation in human disease

Andrew S. McLellan, Robert A. Dubin, Qiang Jing, Shahina B. Maqbool, Raul Olea, Gael Westby, Pilib Ó Broin, Melissa J. Fazzari, Deyou Zheng, Masako Suzuki, John M. Greally

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

There is increasing interest in the role of epigenetic and transcriptional dysregulation in the pathogenesis of a range of human diseases, not just in the best-studied example of cancer. It is, however, quite difficult for an individual investigator to perform these studies, as they involve genome-wide molecular assays combined with sophisticated computational analytical approaches of very large datasets that may be generated from various resources and technologies. In 2008, the Albert Einstein College of Medicine in New York, USA established a Center for Epigenomics to facilitate the research programs of its investigators, providing shared resources for genome-wide assays and for data analysis. As a result, several avenues of research are now expanding, with cancer epigenomics being complemented by studies of the epigenomics of infectious disease and a neuroepigenomics program.

Original languageEnglish
Pages (from-to)33-38
Number of pages6
JournalEpigenomics
Volume1
Issue number1
DOIs
StatePublished - Oct 2009
Externally publishedYes

Keywords

  • Bioinformatics
  • Chromatin
  • Cytosine methylation
  • Epigenetics

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