The efficacy of multiple courses of alefacept in patients with moderate to severe chronic plaque psoriasis

Alan Menter; Jennifer C. Cather; Diane Baker; Harold F. Farber; Mark Lebwohl; Mohamed Darif

doi:10.1016/j.jaad.2005.10.006

The efficacy of multiple courses of alefacept in patients with moderate to severe chronic plaque psoriasis

Alan Menter, Jennifer C. Cather, Diane Baker, Harold F. Farber, Mark Lebwohl, Mohamed Darif

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

Among patients with psoriasis who did not achieve Psoriasis Area and Severity Index 50 during the first course of alefacept therapy, 53% achieved Psoriasis Area and Severity Index 50 during the second course (odds ratio [95% confidence interval] vs placebo 2.30 [1.26-4.19]). Alefacept provided incremental efficacy over 5 successive 12-week treatment courses.

Original language	English
Pages (from-to)	61-63
Number of pages	3
Journal	Journal of the American Academy of Dermatology
Volume	54
Issue number	1
DOIs	https://doi.org/10.1016/j.jaad.2005.10.006
State	Published - Jan 2006

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title = "The efficacy of multiple courses of alefacept in patients with moderate to severe chronic plaque psoriasis",

abstract = "Among patients with psoriasis who did not achieve Psoriasis Area and Severity Index 50 during the first course of alefacept therapy, 53% achieved Psoriasis Area and Severity Index 50 during the second course (odds ratio [95% confidence interval] vs placebo 2.30 [1.26-4.19]). Alefacept provided incremental efficacy over 5 successive 12-week treatment courses.",

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AU - Darif, Mohamed

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AB - Among patients with psoriasis who did not achieve Psoriasis Area and Severity Index 50 during the first course of alefacept therapy, 53% achieved Psoriasis Area and Severity Index 50 during the second course (odds ratio [95% confidence interval] vs placebo 2.30 [1.26-4.19]). Alefacept provided incremental efficacy over 5 successive 12-week treatment courses.

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The efficacy of multiple courses of alefacept in patients with moderate to severe chronic plaque psoriasis

Abstract

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