The Effect of Depression in Chronic Hemodialysis Patients on Inpatient Hospitalization Outcomes

Lili Chan; Sri Lekha Tummalapalli; Rocco Ferrandino; Priti Poojary; Aparna Saha; Kinsuk Chauhan; Girish N. Nadkarni

doi:10.1159/000452750

The Effect of Depression in Chronic Hemodialysis Patients on Inpatient Hospitalization Outcomes

Lili Chan, Sri Lekha Tummalapalli, Rocco Ferrandino, Priti Poojary, Aparna Saha, Kinsuk Chauhan, Girish N. Nadkarni

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Background/Aims: Depression is common in patients with end-stage renal disease (ESRD) on hemodialysis (HD). Although, depression is associated with mortality, the effect of depression on in-hospital outcomes has not been studied as yet. Methods: We analyzed the National Inpatient Sample for trends and outcomes of hospitalizations with depression in patients with ESRD. Results: The proportion of ESRD hospitalizations with depression doubled from 2005 to 2013 (5.01-11.78%). Hospitalized patients on HD with depression were younger (60.47 vs. 62.70 years, p < 0.0001), female (56.93 vs. 47.81%, p < 0.0001), white (44.92 vs. 34.01%, p < 0.0001), and had higher proportion of comorbidities. However, there was a statistically significant lower risk of mortality in HD patients within the top 5 reasons for admissions. Conclusion: There were significant differences in demographics and comorbidities for hospitalized HD patients with depression. Depression was associated with an increased rate of adverse effects in discharged patients, and decreased in-hospital mortality.

Original language	English
Pages (from-to)	226-234
Number of pages	9
Journal	Blood Purification
Volume	43
Issue number	1-3
DOIs	https://doi.org/10.1159/000452750
State	Published - 1 Mar 2017

Keywords

Costs
Depression
End-stage renal disease
Hospitalization
Mortality

Access to Document

10.1159/000452750

Cite this

@article{5e5e2b33fb834686a360400c41a2b31f,

title = "The Effect of Depression in Chronic Hemodialysis Patients on Inpatient Hospitalization Outcomes",

abstract = "Background/Aims: Depression is common in patients with end-stage renal disease (ESRD) on hemodialysis (HD). Although, depression is associated with mortality, the effect of depression on in-hospital outcomes has not been studied as yet. Methods: We analyzed the National Inpatient Sample for trends and outcomes of hospitalizations with depression in patients with ESRD. Results: The proportion of ESRD hospitalizations with depression doubled from 2005 to 2013 (5.01-11.78%). Hospitalized patients on HD with depression were younger (60.47 vs. 62.70 years, p < 0.0001), female (56.93 vs. 47.81%, p < 0.0001), white (44.92 vs. 34.01%, p < 0.0001), and had higher proportion of comorbidities. However, there was a statistically significant lower risk of mortality in HD patients within the top 5 reasons for admissions. Conclusion: There were significant differences in demographics and comorbidities for hospitalized HD patients with depression. Depression was associated with an increased rate of adverse effects in discharged patients, and decreased in-hospital mortality.",

keywords = "Costs, Depression, End-stage renal disease, Hospitalization, Mortality",

author = "Lili Chan and Tummalapalli, {Sri Lekha} and Rocco Ferrandino and Priti Poojary and Aparna Saha and Kinsuk Chauhan and Nadkarni, {Girish N.}",

note = "Publisher Copyright: {\textcopyright} 2017 S. Karger AG, Basel.",

year = "2017",

month = mar,

day = "1",

doi = "10.1159/000452750",

language = "English",

volume = "43",

pages = "226--234",

journal = "Blood Purification",

issn = "0253-5068",

publisher = "S. Karger AG",

number = "1-3",

}

TY - JOUR

T1 - The Effect of Depression in Chronic Hemodialysis Patients on Inpatient Hospitalization Outcomes

AU - Chan, Lili

AU - Tummalapalli, Sri Lekha

AU - Ferrandino, Rocco

AU - Poojary, Priti

AU - Saha, Aparna

AU - Chauhan, Kinsuk

AU - Nadkarni, Girish N.

PY - 2017/3/1

Y1 - 2017/3/1

N2 - Background/Aims: Depression is common in patients with end-stage renal disease (ESRD) on hemodialysis (HD). Although, depression is associated with mortality, the effect of depression on in-hospital outcomes has not been studied as yet. Methods: We analyzed the National Inpatient Sample for trends and outcomes of hospitalizations with depression in patients with ESRD. Results: The proportion of ESRD hospitalizations with depression doubled from 2005 to 2013 (5.01-11.78%). Hospitalized patients on HD with depression were younger (60.47 vs. 62.70 years, p < 0.0001), female (56.93 vs. 47.81%, p < 0.0001), white (44.92 vs. 34.01%, p < 0.0001), and had higher proportion of comorbidities. However, there was a statistically significant lower risk of mortality in HD patients within the top 5 reasons for admissions. Conclusion: There were significant differences in demographics and comorbidities for hospitalized HD patients with depression. Depression was associated with an increased rate of adverse effects in discharged patients, and decreased in-hospital mortality.

AB - Background/Aims: Depression is common in patients with end-stage renal disease (ESRD) on hemodialysis (HD). Although, depression is associated with mortality, the effect of depression on in-hospital outcomes has not been studied as yet. Methods: We analyzed the National Inpatient Sample for trends and outcomes of hospitalizations with depression in patients with ESRD. Results: The proportion of ESRD hospitalizations with depression doubled from 2005 to 2013 (5.01-11.78%). Hospitalized patients on HD with depression were younger (60.47 vs. 62.70 years, p < 0.0001), female (56.93 vs. 47.81%, p < 0.0001), white (44.92 vs. 34.01%, p < 0.0001), and had higher proportion of comorbidities. However, there was a statistically significant lower risk of mortality in HD patients within the top 5 reasons for admissions. Conclusion: There were significant differences in demographics and comorbidities for hospitalized HD patients with depression. Depression was associated with an increased rate of adverse effects in discharged patients, and decreased in-hospital mortality.

KW - Costs

KW - Depression

KW - End-stage renal disease

KW - Hospitalization

KW - Mortality

UR - http://www.scopus.com/inward/record.url?scp=85010876997&partnerID=8YFLogxK

U2 - 10.1159/000452750

DO - 10.1159/000452750

M3 - Article

C2 - 28114133

AN - SCOPUS:85010876997

SN - 0253-5068

VL - 43

SP - 226

EP - 234

JO - Blood Purification

JF - Blood Purification

IS - 1-3

ER -

The Effect of Depression in Chronic Hemodialysis Patients on Inpatient Hospitalization Outcomes

Abstract

Keywords

Access to Document

Fingerprint

Cite this