The effect of age on mitochondrial enzymes respiration

Patricia D. Wilson, Bridget T. Hill, L. M. Franks

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

There was no significant difference between the levels of cytochrome oxidase and malate dehydrogenase in whole liver homogenatcs or in mitochondria isolated from the livers of 6-month-old and 30-month-old C57/BL mice. Little change with age was found in the cytochemical localisation of either enzyme. There were no significant changes in endogenous, state III or state IV respiration of mitochondria isolated from the livers of young and old mice.

Original languageEnglish
Pages (from-to)95-101
Number of pages7
JournalGerontology
Volume21
Issue number2
DOIs
StatePublished - 1975
Externally publishedYes

Keywords

  • Cytochemistry
  • Cytochrome oxidase
  • Homogenate
  • Malate dehydrogenase
  • Mitochondria
  • Mouse liver

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