The Early Detection of Remission in Acute Myelogenous Leukaemia by in Vitro Cultures

G. Spitzer, K. A. Dicke, K. B. Mccredie, B. Barlogie

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Twenty‐eight cases of acute myeloid leukaemia without normal myeloid colony growth in vitro were serially cultured by an in vitro agar culture method during remission induction therapy. Colony formation frequently returned before morphological evidence of remission. Without early return of colony formation drug induced aplasia was prolonged and fatal. Analysis of the pattern of return of in vitro colony forming cells may be of value in designing the chemotherapy schedule.

Original languageEnglish
Pages (from-to)411-418
Number of pages8
JournalBritish Journal of Haematology
Volume35
Issue number3
DOIs
StatePublished - Mar 1977
Externally publishedYes

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