The design and performance of a portable handheld 11CO2 delivery system

Dohyun Kim; David L. Alexoff; Mike Schueller; Ben Babst; Richard Ferrieri; Joanna S. Fowler; David J. Schlyer

doi:10.1016/j.apradiso.2014.09.008

The design and performance of a portable handheld ¹¹CO₂ delivery system

Dohyun Kim
, David L. Alexoff
, Mike Schueller
, Ben Babst
, Richard Ferrieri
, Joanna S. Fowler
, David J. Schlyer

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

We constructed a hand-held device to efficiently trap [¹¹C]CO₂ from the cyclotron target, safely transport up to 3.7GBq (100mCi) doses to remote sites and release it without the need for a liquid cryogen. The system consists of a 180W furnace and a miniature molecular sieve trap (80-100mg; 80-100mesh 13×) placed inside a lead pig weighing 11.1kg. The overall [¹¹C]CO₂ delivery efficiency of the device is ~82% (> 99% trapping efficiency). Radiation dose rates measured at 30cm from the surface of the pig are <43.5μSv/h (5mR/h) up to 2.59GBq (70mCi).

Original language	English
Pages (from-to)	338-343
Number of pages	6
Journal	Applied Radiation and Isotopes
Volume	94
DOIs	https://doi.org/10.1016/j.apradiso.2014.09.008
State	Published - 1 Dec 2014
Externally published	Yes

Keywords

Miniature
PET
Portable
Radiochemistry
[C]CO

Access to Document

10.1016/j.apradiso.2014.09.008

Cite this

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title = "The design and performance of a portable handheld 11CO2 delivery system",

abstract = "We constructed a hand-held device to efficiently trap [11C]CO2 from the cyclotron target, safely transport up to 3.7GBq (100mCi) doses to remote sites and release it without the need for a liquid cryogen. The system consists of a 180W furnace and a miniature molecular sieve trap (80-100mg; 80-100mesh 13×) placed inside a lead pig weighing 11.1kg. The overall [11C]CO2 delivery efficiency of the device is \textasciitilde{}82\% (> 99\% trapping efficiency). Radiation dose rates measured at 30cm from the surface of the pig are <43.5μSv/h (5mR/h) up to 2.59GBq (70mCi).",

keywords = "Miniature, PET, Portable, Radiochemistry, [C]CO",

author = "Dohyun Kim and Alexoff, \{David L.\} and Mike Schueller and Ben Babst and Richard Ferrieri and Fowler, \{Joanna S.\} and Schlyer, \{David J.\}",

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doi = "10.1016/j.apradiso.2014.09.008",

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T1 - The design and performance of a portable handheld 11CO2 delivery system

AU - Kim, Dohyun

AU - Alexoff, David L.

AU - Schueller, Mike

AU - Babst, Ben

AU - Ferrieri, Richard

AU - Fowler, Joanna S.

AU - Schlyer, David J.

PY - 2014/12/1

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AB - We constructed a hand-held device to efficiently trap [11C]CO2 from the cyclotron target, safely transport up to 3.7GBq (100mCi) doses to remote sites and release it without the need for a liquid cryogen. The system consists of a 180W furnace and a miniature molecular sieve trap (80-100mg; 80-100mesh 13×) placed inside a lead pig weighing 11.1kg. The overall [11C]CO2 delivery efficiency of the device is ~82% (> 99% trapping efficiency). Radiation dose rates measured at 30cm from the surface of the pig are <43.5μSv/h (5mR/h) up to 2.59GBq (70mCi).

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KW - [C]CO

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