The coronary artery surgery study (CASS) - a randomized trial and a registry

T. Killip

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


In 1973 the National Heart Lung and Blood Institute organized the Coronary Artery Surgery Study (CASS) including a patient registry and a randomized trial designed to compare medical and surgical therapy in patients with coronary artery disease. This study is discussed in detail and compared with two further large randomized trials of coronary artery bypass surgery, the US Veterans Administration Trial (VA) and the European Cooperative Surgical Study (ECSS). Although there are many differences between these three studies, their similarities warrant some conclusions on the improvement of survival in certain high risk patients, protection against myocardial infarction, the deterioration of graft patency, and the postponement of surgery in low risk patients.

Original languageEnglish
Pages (from-to)79-85
Number of pages7
JournalZeitschrift fur Kardiologie
Issue numberSUPPL. 6
StatePublished - 1985
Externally publishedYes


Dive into the research topics of 'The coronary artery surgery study (CASS) - a randomized trial and a registry'. Together they form a unique fingerprint.

Cite this