TY - JOUR
T1 - The convergence of neuropsychological testing and clinical ratings of cognitive impairment in patients with schizophrenia
AU - Harvey, Philip D.
AU - Serper, Mark R.
AU - White, Leonard
AU - Parrella, Michael J.
AU - McGurk, Susan R.
AU - Moriarty, Patrick J.
AU - Bowie, Christopher
AU - Vadhan, Nehal
AU - Friedman, Joseph
AU - Davis, Kenneth L.
N1 - Funding Information:
From the Mount Sinai School of Medicine; Hofstra University; and the New York University School of Medicine, New York, NY. Supported by the assessment core (Philip D. Harvey, PI) of the Mt. Sinai Mental Health Clinical Research Center (Kenneth L. Davis, PI), and the VISN 3 MIRECC from Department of Veterans Affairs. Address reprint requests to Philip D. Harvey, Ph.D., Department of Psychiatry, Box 1229, Mt. Sinai School of Medicine, New York, NY 10029. Copyright © 2001 by W.B. Saunders Company 0010-440X/01/4204-0006$35.00/0 doi:10.1053/comp.2001.24587
PY - 2001
Y1 - 2001
N2 - This study examined the relationship between clinical rating of cognitive symptoms and performance on neuropsychological tests in acute and chronic samples of patients with schizophrenia. Two separate studies examined patients who varied widely in their lifetime functional outcome, including 263 elderly poor-outcome inpatients and 20 acutely admitted patients. In the first study, six cognitive performance measures were collected, and in the second study, five different measures were collected. Correlations with different symptom models of cognitive and negative symptoms were examined. In both samples, cognitive symptoms were never more highly correlated with cognitive test performance than with negative symptoms. When cognitive and negative symptom ratings were combined, they never accounted for as much as half of the variance in performance on the cognitive tests in both samples. These data suggest that clinical assessment of symptoms is not a viable alternative to neuropsychological testing to obtain information about cognitive functioning in schizophrenia. These results may also be specific to the clinical rating scale used, the Positive and Negative Syndrome Scale (PANSS).
AB - This study examined the relationship between clinical rating of cognitive symptoms and performance on neuropsychological tests in acute and chronic samples of patients with schizophrenia. Two separate studies examined patients who varied widely in their lifetime functional outcome, including 263 elderly poor-outcome inpatients and 20 acutely admitted patients. In the first study, six cognitive performance measures were collected, and in the second study, five different measures were collected. Correlations with different symptom models of cognitive and negative symptoms were examined. In both samples, cognitive symptoms were never more highly correlated with cognitive test performance than with negative symptoms. When cognitive and negative symptom ratings were combined, they never accounted for as much as half of the variance in performance on the cognitive tests in both samples. These data suggest that clinical assessment of symptoms is not a viable alternative to neuropsychological testing to obtain information about cognitive functioning in schizophrenia. These results may also be specific to the clinical rating scale used, the Positive and Negative Syndrome Scale (PANSS).
UR - http://www.scopus.com/inward/record.url?scp=0034953316&partnerID=8YFLogxK
U2 - 10.1053/comp.2001.24587a
DO - 10.1053/comp.2001.24587a
M3 - Article
C2 - 11458305
AN - SCOPUS:0034953316
SN - 0010-440X
VL - 42
SP - 306
EP - 313
JO - Comprehensive Psychiatry
JF - Comprehensive Psychiatry
IS - 4
ER -