The Contents of Herbal and Dietary Supplements Implicated in Liver Injury in the United States Are Frequently Mislabeled

Victor Navarro; Bharathi Avula; Ikhlas Khan; Manisha Verma; Leonard Seeff; Jose Serrano; Andrew Stolz; Robert Fontana; Jawad Ahmad

doi:10.1002/hep4.1346

The Contents of Herbal and Dietary Supplements Implicated in Liver Injury in the United States Are Frequently Mislabeled

Victor Navarro, Bharathi Avula, Ikhlas Khan, Manisha Verma, Leonard Seeff, Jose Serrano, Andrew Stolz, Robert Fontana, Jawad Ahmad

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

The U.S. Drug Induced Liver Injury Network assayed the contents of herbal and dietary supplements collected from patients enrolled into its prospective study. The aim was to determine the accuracy of product labels, and to identify known hepatotoxins. Using high-performance liquid chromatography coupled with mass spectrometry to assay 272 product, 51% were found to be mislabeled; that is, to have chemical contents that did not match the label. Appearance enhancement, sexual performance, and weight loss products were most commonly mislabeled. Whether the mislabeling contributed to liver injury is under study; however, the high mislabeling rate underscores the need for more stringent regulation of supplements.

Original language	English
Pages (from-to)	792-794
Number of pages	3
Journal	Hepatology Communications
Volume	3
Issue number	6
DOIs	https://doi.org/10.1002/hep4.1346
State	Published - Jun 2019

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10.1002/hep4.1346

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title = "The Contents of Herbal and Dietary Supplements Implicated in Liver Injury in the United States Are Frequently Mislabeled",

abstract = "The U.S. Drug Induced Liver Injury Network assayed the contents of herbal and dietary supplements collected from patients enrolled into its prospective study. The aim was to determine the accuracy of product labels, and to identify known hepatotoxins. Using high-performance liquid chromatography coupled with mass spectrometry to assay 272 product, 51% were found to be mislabeled; that is, to have chemical contents that did not match the label. Appearance enhancement, sexual performance, and weight loss products were most commonly mislabeled. Whether the mislabeling contributed to liver injury is under study; however, the high mislabeling rate underscores the need for more stringent regulation of supplements.",

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AU - Khan, Ikhlas

AU - Verma, Manisha

AU - Seeff, Leonard

AU - Serrano, Jose

AU - Stolz, Andrew

AU - Fontana, Robert

AU - Ahmad, Jawad

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The Contents of Herbal and Dietary Supplements Implicated in Liver Injury in the United States Are Frequently Mislabeled

Abstract

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