@article{ac5d8fdd48d64ded9bb9e60f0acc6b4a,
title = "The Consortium for Food Allergy Research (CoFAR): The first generation",
abstract = "The Consortium for Food Allergy Research (CoFAR) was established by the National Institute of Allergy and Infectious Diseases in 2005 as a collaborative research program bringing together centers focused on the study of food allergy. CoFAR was charged with developing studies to better understand the pathogenesis and natural history of food allergy, as well as potential approaches to the treatment of food allergy. In its first iteration an observational study of infants with milk and egg allergy was established, and studies of oral immunotherapy for egg allergy and sublingual immunotherapy for peanut allergy were initiated, as was a phase 1 study of a recombinant peanut protein vaccine. CoFAR was renewed in 2010 for an additional 5-year period during which the initial observational study was continued, a study of eosinophilic esophagitis was initiated, and new therapeutic trials were established to study epicutaneous immunotherapy for peanut allergy and to compare the safety and efficacy of egg oral immunotherapy to the ingestion of baked egg for the treatment of egg allergy. The results of these efforts will be reviewed in this rostrum, with a brief look to the future of CoFAR.",
keywords = "Food allergy, egg allergy, epicutaneous immunotherapy, immunotherapy, oral immunotherapy, peanut allergy, sublingual immunotherapy",
author = "Sampson, {Hugh A.} and Berin, {M. Cecilia} and Marshall Plaut and Sicherer, {Scott H.} and Stacie Jones and Burks, {A. Wesley} and Robert Lindblad and Leung, {Donald Y.M.} and Wood, {Robert A.}",
note = "Funding Information: Disclosure of potential conflict of interest: H. A. Sampson reports being a part-time employee of DBV Technologies; receiving consultant fees from N-Fold, LLC and UCB SA, and royalties from UpToDate and Elsevier; holding stock options in DBV Technologies and N-FOLD; and receiving grants to his Institution from the National Institutes of Health, National Institute of Allergy and Infectious Diseases, and Food Allergy Research & Education. S. H. Sicherer receives grant support to his institution from the National Institute of Allergy and Infectious Diseases, Food Allergy Research and Education, and HAL Allergy; royalties from UpToDate and Johns Hopkins University Press; and honorarium from the American Academy of Allergy, Asthma & Immunology for his role as Deputy Editor of the Journal of Allergy and Clinical Immunology: In Practice. S. Jones receives grant support to her institution from the National Institute of Allergy and Infectious Diseases, DBV Technologies, Food Allergy Research and Education, Aimmune, Astellas, and personal fees from Food Allergy Research and Education, Emmes Corporation, and Aimmune. A. W. Burks receives grant support to his institution from the National Institutes of Health, Food Allergy Research & Education, and Allergen Research Corporation; royalties from UpToDate; consulting honorariums from Aravax, Astella Pharma Global Development, DBV Technologies and N-Fold, LLC, as well as Aimmune Therapeutics, Consortia TX, Inc, Intrommune Therapeutics, and Prota Therapeutics for his service on their respective Scientific Advisory Boards. R. Lindblad is employed by Emmes Corporation. D. Y. M. Leung receives grant support to his institution from the National Institute of Allergy and Infectious Diseases and is Chairman of the DSMC for Aimmune. R. A. Wood receives grant support to his institution from the National Institute of Allergy and Infectious Diseases, DBV Technologies, HAL Allergy, Regeneron, Aimmune, and Astellas; royalties from UpToDate; and personal fees from the American Academy of Allergy, Asthma & Immunology for his role as President and as Associate Editor of the Journal of Allergy and Clinical Immunology. The rest of the authors declare that they have no relevant conflicts of interest. Publisher Copyright: {\textcopyright} 2018 American Academy of Allergy, Asthma & Immunology",
year = "2019",
month = feb,
doi = "10.1016/j.jaci.2018.12.989",
language = "English",
volume = "143",
pages = "486--493",
journal = "Journal of Allergy and Clinical Immunology",
issn = "0091-6749",
publisher = "Mosby Inc.",
number = "2",
}