The claustrum is a target for projections from the supramammillary nucleus in the rat

Marie Barbier; Pierre Yves Risold

doi:10.1016/j.neuroscience.2019.03.045

The claustrum is a target for projections from the supramammillary nucleus in the rat

Marie Barbier
, Pierre Yves Risold

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Injection of the anterograde tracer Phaseolus vulgaris leucoagglutinin (PHAL) into the rat rostral and caudal supramammillary nucleus (SUM) provided expected patterns of projections into the hippocampus and the septal region. In addition, unexpectedly intense projections were observed into the claustrum defined by parvalbumin expression. Injections of the retrograde tracer fluorogold (FG) into the hippocampus and the region of the claustrum showed that the cells of origin of these projections distributed similarly within the borders of the SUM. The SUM is usually involved in control of hippocampal theta activity, but the observation of intense projections into the claustrum indicates that it may also influence isocortical processes. Therefore, the SUM may coordinate sensory processing in the isocortex with memory formation in the hippocampus.

Original language	English
Pages (from-to)	261-275
Number of pages	15
Journal	Neuroscience
Volume	409
DOIs	https://doi.org/10.1016/j.neuroscience.2019.03.045
State	Published - 15 Jun 2019
Externally published	Yes

Keywords

dentate gyrus
parvalbumin
salience
septum
tract tracing

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10.1016/j.neuroscience.2019.03.045

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title = "The claustrum is a target for projections from the supramammillary nucleus in the rat",

abstract = "Injection of the anterograde tracer Phaseolus vulgaris leucoagglutinin (PHAL) into the rat rostral and caudal supramammillary nucleus (SUM) provided expected patterns of projections into the hippocampus and the septal region. In addition, unexpectedly intense projections were observed into the claustrum defined by parvalbumin expression. Injections of the retrograde tracer fluorogold (FG) into the hippocampus and the region of the claustrum showed that the cells of origin of these projections distributed similarly within the borders of the SUM. The SUM is usually involved in control of hippocampal theta activity, but the observation of intense projections into the claustrum indicates that it may also influence isocortical processes. Therefore, the SUM may coordinate sensory processing in the isocortex with memory formation in the hippocampus.",

keywords = "dentate gyrus, parvalbumin, salience, septum, tract tracing",

author = "Marie Barbier and Risold, \{Pierre Yves\}",

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doi = "10.1016/j.neuroscience.2019.03.045",

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T1 - The claustrum is a target for projections from the supramammillary nucleus in the rat

AU - Barbier, Marie

AU - Risold, Pierre Yves

PY - 2019/6/15

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N2 - Injection of the anterograde tracer Phaseolus vulgaris leucoagglutinin (PHAL) into the rat rostral and caudal supramammillary nucleus (SUM) provided expected patterns of projections into the hippocampus and the septal region. In addition, unexpectedly intense projections were observed into the claustrum defined by parvalbumin expression. Injections of the retrograde tracer fluorogold (FG) into the hippocampus and the region of the claustrum showed that the cells of origin of these projections distributed similarly within the borders of the SUM. The SUM is usually involved in control of hippocampal theta activity, but the observation of intense projections into the claustrum indicates that it may also influence isocortical processes. Therefore, the SUM may coordinate sensory processing in the isocortex with memory formation in the hippocampus.

AB - Injection of the anterograde tracer Phaseolus vulgaris leucoagglutinin (PHAL) into the rat rostral and caudal supramammillary nucleus (SUM) provided expected patterns of projections into the hippocampus and the septal region. In addition, unexpectedly intense projections were observed into the claustrum defined by parvalbumin expression. Injections of the retrograde tracer fluorogold (FG) into the hippocampus and the region of the claustrum showed that the cells of origin of these projections distributed similarly within the borders of the SUM. The SUM is usually involved in control of hippocampal theta activity, but the observation of intense projections into the claustrum indicates that it may also influence isocortical processes. Therefore, the SUM may coordinate sensory processing in the isocortex with memory formation in the hippocampus.

KW - dentate gyrus

KW - parvalbumin

KW - salience

KW - septum

KW - tract tracing

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DO - 10.1016/j.neuroscience.2019.03.045

M3 - Article

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AN - SCOPUS:85065035596

SN - 0306-4522

VL - 409

SP - 261

EP - 275

JO - Neuroscience

JF - Neuroscience

ER -

The claustrum is a target for projections from the supramammillary nucleus in the rat

Abstract

Keywords

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